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Sunday, November 25, 2012

Ketogenic diet slows progression of cancer...

...in 5 out of 9 patients who exhibited the highest degree of ketosis measured by a level of beta hydroxy butyrate.

The degree of cancer progression slow down or remission correlated with the degree of ketosis and degree of ketosis correlated inversely with the level of insulin.

The study lasted 26-28 days and involved only nine patients who completed the study, all of whom begun with rapidly progressing advanced and incurable cancers.

Fig 2 (part, 1 out of 4 graphs) from the study. β-OH butyrate
(beta hydroxy butyrate) represent a degree of ketosis.

"Targeting insulin inhibition as a metabolic therapy in advanced cancer: A pilot safety and feasibility dietary trial in 10 patients", Eugene J. Fine et al., Nutrition, 1028-1035,2012

Comments:

It is interesting to note that, contrary to a myth about keto diets being supposedly harmful for kidneys,  not only it did not worsen the markers, but improved kidney filtration of one of the patients!

It is important to keep in mind that stopping of a disease progression is not the same as curing it. Ketogenic diet seems to help but I do not consider it to be a universal cure for cancer (it does however cure t2 diabetes!).

Heretic

3 comments :

Zorica Vuletic said...

I agree with you about ketogenic diets curing T2D.

I wonder though if a person has let their T2D so out of hand that they are dependent on insulin, I am not sure if that level is 'cureable' and only treatable as far as needing less insulin is concerned (basically they put themselves on the same path as T1D at this point).

Of course in both cases, ketogenic diet is still the therapeutic go-to. Just me thinking aloud.

Stan Bleszynski said...

It would likely cure t2 even in an advanced stage, but it would probably take a long time (many years, more than 5). However, if a person is very old there may be other issues related to compliance, habits and food tolerances.

I met once a diabetic t2, a man in his 50-ties, in Toronto who had his foot scheduled for amputation, and recovered 100% on a ketogenic diet. On the same meeting, I had a chance to meet people who also cured advanced asthma, intestinal allergies and advanced cardiovascular diseases.

According to Dr. Kwasniewski of Optimal Diet, it would also allow many if not most patients with t1 diabetes to live normal life without insulin injections, though it would not cure it. Most t1 diabetics still produce some insulin, about 10%, which is sufficient on a carefully formulated low carb high fat diet.

Zorica Vuletic said...

Thanks for the clear response. It makes sense.